PRECLINICAL SERVICES - CLINICAL SERVICES PRECISION MEDICINE

PRECLINICAL SERVICES

 

Ultra-Deep Phenotynotyping of Immune Cells

High parameter single cell analysis by Chipcytometry has proven to a powerful tool to investigate target selection and validation and to elucidate drug mechanism of action. Typical Chipcytomery applications are:

  • Deep Cell Immune Cell Phenotyping (>40 parameters)
  • Cell Cycle Analysis
  • Mode of Action, Target Engagement
  • Cell Signaling
  • Intracellular Cytokine Secretion
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Roesner et al. Journal of Investigative Dermatology 2015: Der p1 and Der p2-specific T cells display a Th2, Th17, and Th2/Th17 phenotype in atopic dermatitis.

CLINICAL SERVICES

 

Long-Term Sample Storage and Re-Interrogation

In a clinical trial setting conventional Flow Cytometry is often limited in terms of sample stability, inter-lab variations, inter-operator variability and instrument drift. Chipcytometry enables sample stability for analysis and re-interrogation for about 24 months.

Chipcytometry is the only cytometry technology enabling global clinical trial support using a single instrument and validated automated gating algorithms eliminates unwanted noise from your data sets.

Using ZellSafeā„¢ chips, clinical trial samples are biobanked after analysis, enabling re-interrogation of patient samples after the study is completed.

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PRECISION MEDICINE

 

Companion Diagnostic Development

Disruptive Chipcytometry helps you identify predictive biomarkers, develop and deploy diagnostic tests, and engage the most appropriate patient populations to demonstrate the safety and efficacy of your therapeutic products.

Our experience will help you to avoid obstacles and optimize your path to developing new personalized medicines and companion diagnostics and accelerate the path to decision biomarkers supporting your drug development programs.

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